发明授权
- 专利标题： Recombinant antibody and antibody fragment
- 专利标题（中）： 重组抗体和抗体片段
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申请号： US09796744申请日： 2001-03-02
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公开(公告)号： US06989145B2公开(公告)日： 2006-01-24
- 发明人: Kenya Shitara , Nobuo Hanai , Emi Shoji , Mikiko Sakurada , Akiko Furuya , Kazuyasu Nakamura , Rinpei Niwa , Kenji Shibata , Motoo Yamasaki
- 申请人： Kenya Shitara , Nobuo Hanai , Emi Shoji , Mikiko Sakurada , Akiko Furuya , Kazuyasu Nakamura , Rinpei Niwa , Kenji Shibata , Motoo Yamasaki
- 申请人地址： JP Tokyo
- 专利权人： Kyowa Hakko Kogyo Co., Ltd.
- 当前专利权人： Kyowa Hakko Kogyo Co., Ltd.
- 当前专利权人地址： JP Tokyo
- 代理机构： Fitzpatrick, Cella, Harper & Scinto
- 优先权： JPP.2000-059508 20000303; JPP.2000-401563 20001228
- 主分类号： C07K16/28
- IPC分类号： C07K16/28 ; C12P21/00 ; A61K39/00 ; G01N33/53
摘要：
A recombinant antibody or the antibody fragment thereof which specifically reacts with an extracellular domain of human CCR4; a DNA which encodes the recombinant antibody or the antibody fragment thereof; a method for producing the recombinant antibody or the antibody fragment thereof; a method for immunologically detecting CCR4, a method for immunologically detecting a cell which expressed CCR4 on the cell surface, a method for depleting a cell which expresses CCR4 on the cell surface, and a method for inhibiting production of Th2 cytokine, which comprise using the recombinant antibody according or antibody fragment thereof; a therapeutic or diagnostic agent for Th2-mediated immune diseases; and a therapeutic or diagnostic agent for a blood cancer.
公开/授权文献
- US20020098527A1 Gene recombinant antibody and antibody fragment thereof 公开/授权日：2002-07-25
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