发明授权
- 专利标题: sPLA2 inhibitors
- 专利标题(中): sPLA2抑制剂
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申请号: US10450745申请日: 2001-12-06
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公开(公告)号: US06992100B2公开(公告)日: 2006-01-31
- 发明人: Douglas Wade Beight , Michael Dean Kinnick , Ho-Shen Lin , John Michael Morin, Jr. , Michael Enrico Richett , Daniel Jon Sall , Jason Scott Sawyer , John David Jandzinski
- 申请人: Douglas Wade Beight , Michael Dean Kinnick , Ho-Shen Lin , John Michael Morin, Jr. , Michael Enrico Richett , Daniel Jon Sall , Jason Scott Sawyer , John David Jandzinski
- 申请人地址: US IN Indianapolis
- 专利权人: Eli Lilly and Company
- 当前专利权人: Eli Lilly and Company
- 当前专利权人地址: US IN Indianapolis
- 代理商 Francis O. Ginah
- 国际申请: PCT/US01/43186 WO 20011206
- 国际公布: WO02/50029 WO 20020627
- 主分类号: A61K31/403
- IPC分类号: A61K31/403 ; C07D209/56
摘要:
A novel class of tetracyclic compounds is disclosed together with the use of such compounds for inhibiting sPLA2 mediated release of fatty acids for treatment of Inflammatory Diseases such as septic shock.
公开/授权文献
- US20040092543A1 Novel spla2 inhibitors 公开/授权日:2004-05-13