发明授权
- 专利标题： Process for the preparation of sulphonamide-substituted imidazotriazinones
- 专利标题（中）： 磺酰胺取代的咪唑并三嗪酮的制备方法
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申请号： US11124452申请日： 2005-05-05
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公开(公告)号： US06998483B2公开(公告)日： 2006-02-14
- 发明人: Marc Nowakowski , Reinhold Gehring , Werner Heilmann , Karl-Heinz Wahl
- 申请人： Marc Nowakowski , Reinhold Gehring , Werner Heilmann , Karl-Heinz Wahl
- 申请人地址： DE Leverkusen
- 专利权人： Bayer HealthCare Aktiengesellschaft
- 当前专利权人： Bayer HealthCare Aktiengesellschaft
- 当前专利权人地址： DE Leverkusen
- 代理商 Susan M. Pellegrino
- 优先权： DE10063108 20001218
- 主分类号： C07D487/04
- IPC分类号： C07D487/04
摘要：
The present invention relates to a process for the preparation of sulphonamide-substituted imidazotriazinones of the general formula (I) characterized in that compounds of the formula (II) are reacted with sulphuric acid and the products obtained are then reacted with thionyl chloride and converted in situ in an inert solvent using an amine into the compounds according to the invention and, if appropriate, reacted to give the corresponding salts, hydrates or N-oxides.
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