- 专利标题: Ionic molecular conjugates of N-acylated derivatives of poly(2-amino-2-deoxy-D-glucose) and polypeptides
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申请号: US10900220申请日: 2004-07-27
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公开(公告)号: US07005420B2公开(公告)日: 2006-02-28
- 发明人: Shalaby W. Shalaby , Ruth M. Russell , Jacques-Pierre Moreau , Steven A. Jackson , Francis X. Ignatious
- 申请人: Shalaby W. Shalaby , Ruth M. Russell , Jacques-Pierre Moreau , Steven A. Jackson , Francis X. Ignatious
- 申请人地址: IE Dublin
- 专利权人: Ipsen Manufacturing Ireland Limited
- 当前专利权人: Ipsen Manufacturing Ireland Limited
- 当前专利权人地址: IE Dublin
- 代理机构: Fish & Richardson
- 代理商 Brian R. Morrill; Alan F. Feeney
- 主分类号: A61K38/00
- IPC分类号: A61K38/00
摘要:
A copolymer comprising an N-acylated derivative, and a composition comprising said copolymer and a polypeptide, said polypeptide comprising at least one effective ionogenic amine, wherein at least 50 percent, by weight, of said polypeptide present in said composition is ionically bound to said polymer.
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