发明授权
US07009087B1 Compositions and methods for altering the disulfide status of proteins
失效
用于改变蛋白质二硫键状态的组合物和方法
- 专利标题: Compositions and methods for altering the disulfide status of proteins
- 专利标题(中): 用于改变蛋白质二硫键状态的组合物和方法
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申请号: US10005429申请日: 2001-12-03
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公开(公告)号: US07009087B1公开(公告)日: 2006-03-07
- 发明人: Vincent Sewalt , Craig Hastings , Robert Meeley , Sabine Susanne Hantke , Rudolf Jung , John D. Everard , Stephen M. Allen
- 申请人: Vincent Sewalt , Craig Hastings , Robert Meeley , Sabine Susanne Hantke , Rudolf Jung , John D. Everard , Stephen M. Allen
- 申请人地址: US IA Des Moines
- 专利权人: Pioneer Hi-Bred International, Inc.
- 当前专利权人: Pioneer Hi-Bred International, Inc.
- 当前专利权人地址: US IA Des Moines
- 代理机构: Alston & Bird LLP
- 主分类号: C12N15/29
- IPC分类号: C12N15/29 ; C12N15/82 ; C12N15/87 ; A01H5/00 ; A01H5/10
摘要:
Compositions and methods for the alteration of the disulfide status of plant proteins are provided. Novel nucleotide molecules, comprising nucleotide sequences for thioredoxin h and NADPH-thioredoxin reductase, and the proteins encoded thereby are provided. The nucleotide sequences can be used to transform plants alone or in combination with other sequences, such as sequences encoding NADPH generating enzymes, to manipulate the thioredoxin h system and alter the protein disulfide status in plants. Transformed plants, plant cells, plant tissues, seed and grain are provided.
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