A surgical instrument for the dissection of bone and other tissue includes a spindle, a dissection tool and a male member carried by the spindle. The spindle includes a cavity. The dissection tool is releasably received in the cavity. The dissection tool extends along an axis and includes a first end and a second end with the first end having a cutting element and a second end having a generally cylindrical cross-section and a centrally located aperture partially extending along the axis. The male member is carried by the spindle and extends into the aperture of the dissection tool. The cavity may define a drive portion and a tool receiving aperture. One or more alignment projections may extend from the drive portion into the tool receiving aperture.