- 专利标题: Cathepsin cysteine protease inhibitors
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申请号: US10469430申请日: 2002-03-01
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公开(公告)号: US07012075B2公开(公告)日: 2006-03-14
- 发明人: Petpihoon Prasit , Christopher Ian Bayly , Joel Stephane Robichaud , W. Cameron Black , Eduardo L. Setti , Robert M. Rydzewski , James T. Palmer
- 申请人: Petpihoon Prasit , Christopher Ian Bayly , Joel Stephane Robichaud , W. Cameron Black , Eduardo L. Setti , Robert M. Rydzewski , James T. Palmer
- 申请人地址: US NJ Rahway US CA South San Francisco
- 专利权人: Merck & Co., Inc.,Axys Pharmaceuticals, Inc.
- 当前专利权人: Merck & Co., Inc.,Axys Pharmaceuticals, Inc.
- 当前专利权人地址: US NJ Rahway US CA South San Francisco
- 代理商 Nicole M. Beeler; Mark R. Dāniel
- 国际申请: PCT/US02/06533 WO 20020301
- 国际公布: WO02/069901 WO 20020912
- 主分类号: A61K31/495
- IPC分类号: A61K31/495 ; A61K31/44 ; A61K31/275 ; C07D413/00 ; C07C255/00
摘要:
This invention relates to a novel class of compounds which are cysteine protease inhibitors, including but not limited to, inhibitors of cathepsins K, L, S and B. These compounds are useful for treating diseases in which inhibition of bone resorption is indicated, such as osteoporosis.
公开/授权文献
- US20040198982A1 Cathepsin cysteine protease inhibitors 公开/授权日:2004-10-07
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