A universal mobile phone adapter device for a vehicle appliance operable for enabling a user to talk hands-free on a mobile phone during a phone call between the mobile phone and a telephone of another party when the mobile phone is electronically connected to the vehicle appliance. The adapter device includes a universal vehicle adapter base integrated in the interior of the vehicle. The adapter base is electronically connected to the vehicle appliance. The adapter device includes first and second adapter sleeves which are removably receivable one at a time within the adapter base. The adapter sleeves include respective first and second mobile phone receiving areas for removably receiving first and second mobile phones having different configurations. The adapter sleeves and the adapter base electronically connect the mobile phones to the vehicle appliance when the adapter sleeves receive the respective mobile phones and the adapter base receives the adapter sleeves.