- 专利标题： Isolated nucleic acid molecule coding for tumor rejection antigen precursors MAGE-C1 and MAGE-C2 and uses thereof
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申请号： US10160237申请日： 2002-06-04
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公开(公告)号： US07022819B2公开(公告)日： 2006-04-04
- 发明人: Sophie Lucas , Charles De Smet , Thierry Boon-Falleur
- 申请人： Sophie Lucas , Charles De Smet , Thierry Boon-Falleur
- 申请人地址： US NY New York
- 专利权人： Ludwig Institute for Cancer Research
- 当前专利权人： Ludwig Institute for Cancer Research
- 当前专利权人地址： US NY New York
- 代理机构： Fulbright & Jaworski
- 主分类号： C07K14/00
- IPC分类号： C07K14/00
摘要：
The invention relates to isolated nucleic acid molecules which code for antigens expressed by tumor cells which maybe recognized by cytotoxic T cells, leading to lysis of the tumor cells which express it. This invention also relates to vectors which are designed to encode the antigen expressed by tumor cells and also to cells transfected by the nucleic acid molecules or vectors which comprise the nucleic acid molecules. Various therapeutic and diagnostic uses arising out of the properties of the nucleic acid molecules and the antigens for which these code are also part of this invention.
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