Invention Grant
- Patent Title: Compounds exhibiting X-type sPLA2 inhibiting effect
- Patent Title (中): 表现出X型sPLA2抑制作用的化合物
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Application No.: US10311282Application Date: 2001-06-27
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Publication No.: US07026318B2Publication Date: 2006-04-11
- Inventor: Tomoyuki Ogawa , Kaoru Seno , Kohji Hanasaki , Minoru Ikeda , Takashi Ono
- Applicant: Tomoyuki Ogawa , Kaoru Seno , Kohji Hanasaki , Minoru Ikeda , Takashi Ono
- Applicant Address: JP Osaka
- Assignee: Shionogi & Co., Ltd.
- Current Assignee: Shionogi & Co., Ltd.
- Current Assignee Address: JP Osaka
- Agency: Wenderoth, Lind & Ponack, L.L.P.
- Priority: JP2000-195430 20000629
- International Application: PCT/JP01/05479 WO 20010627
- International Announcement: WO02/00621 WO 20020103
- Main IPC: A01N43/58
- IPC: A01N43/58 ; A01N43/60 ; A61K31/495 ; A61K31/50 ; C07D241/36
Abstract:
A compound represented by the general formula: wherein R20 is —CH2COOH and the like; R21 is —COCONH2 and the like; R22 is C4–C6 alkyl; and the like; R23 is —CH2—R18 wherein R18 is aryl and the like; R24 is hydrogen or C1–C6 alkyl and the like; an optical active compound, a prodrug thereof, or a pharmaceutically acceptable salt, or a solvate having type X sPLA2 inhibitory effect was found.
Public/Granted literature
- US20030181454A1 Compounds exhibiting x-type spla2 inibiting effect Public/Granted day:2003-09-25
Information query
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