发明授权
- 专利标题: Compounds
- 专利标题(中): 化合物
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申请号: US10130019申请日: 2000-11-20
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公开(公告)号: US07026336B1公开(公告)日: 2006-04-11
- 发明人: David Kenneth Dean , Peter John Lovell , Andrew Kenneth Takle
- 申请人: David Kenneth Dean , Peter John Lovell , Andrew Kenneth Takle
- 申请人地址: GB Brentford
- 专利权人: SmithKline Beecham p.l.c.
- 当前专利权人: SmithKline Beecham p.l.c.
- 当前专利权人地址: GB Brentford
- 代理商 Dara L. Dinner; Stephen Venetianer; Charles M. Kinzig
- 国际申请: PCT/GB00/04413 WO 20001120
- 国际公布: WO01/38324 WO 20010531
- 主分类号: C07D401/04
- IPC分类号: C07D401/04 ; C07D401/14 ; C07D403/04 ; A61K31/4439 ; A61P9/10
摘要:
Compounds of formula (I) wherein X is O, CH2, S or NH, or the moiety X—R1 is hydrogen; V is CH or N; Y is NR10R11, NR10C(Z)NR10R11, NR10COOR11 or NR10SO2R11; Ar is phenyl or a 5- or 6-membered heteroaryl ring either of which may be optionally substituted; n is 0, 1, 2, 3 or 4; and R1, R2, R3, R4, R10 and R11 have the meanings given in the description; and pharmaceutically acceptable salt thereof.