发明授权
US07033745B1 Use of gluclose-6-phosphate isomerase and antibodies thereto for the diagnosis and therapy of arthritis, and test of anti-arthritic compounds
有权
使用葡萄糖-6-磷酸异构酶及其抗体进行关节炎的诊断和治疗,并测定抗关节炎化合物
- 专利标题: Use of gluclose-6-phosphate isomerase and antibodies thereto for the diagnosis and therapy of arthritis, and test of anti-arthritic compounds
- 专利标题(中): 使用葡萄糖-6-磷酸异构酶及其抗体进行关节炎的诊断和治疗,并测定抗关节炎化合物
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申请号: US09959230申请日: 2000-04-21
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公开(公告)号: US07033745B1公开(公告)日: 2006-04-25
- 发明人: Christophe Benoist , Isao Matsumoto , Anne-Sophie Korganow , Diane Mathis , Mariana Maccioni , Hong Ji
- 申请人: Christophe Benoist , Isao Matsumoto , Anne-Sophie Korganow , Diane Mathis , Mariana Maccioni , Hong Ji
- 申请人地址: FR Paris
- 专利权人: Institut National de la Sante et de la Rescherche Medicale (Inserm)
- 当前专利权人: Institut National de la Sante et de la Rescherche Medicale (Inserm)
- 当前专利权人地址: FR Paris
- 代理机构: Foley & Lardner LLP
- 国际申请: PCT/IB00/00600 WO 20000421
- 国际公布: WO00/64469 WO 20001102
- 主分类号: C12Q1/00
- IPC分类号: C12Q1/00
摘要:
The present invention relates to the use of antibodies against glucose-6-phosphate isomerase and like protein for diagnosis of arthritis and the use of said protein for treatment of arthritis. It is also aimed at a process for isolating monoclonal antibodies capable of transferring arthritis and antibodies thereof, as well as a method for determining the anti-arthritic potential of a composition.
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