- 专利标题： Medicinal compositions for preventing and treating hemorrhagic diseases associating thrombopathy
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申请号： US10168727申请日： 2000-12-21
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公开(公告)号： US07033994B2公开(公告)日： 2006-04-25
- 发明人: Tatsuya Araki , Kazuhiko Tomokiyo , Yasushi Nakatomi , Kaori Teshima , Tomoko Watanabe , Tomohiro Nakagaki
- 申请人： Tatsuya Araki , Kazuhiko Tomokiyo , Yasushi Nakatomi , Kaori Teshima , Tomoko Watanabe , Tomohiro Nakagaki
- 专利权人： Juridical Foundation the Chemo-Sero-Therapeutic Research Institute
- 当前专利权人： Juridical Foundation the Chemo-Sero-Therapeutic Research Institute
- 代理机构： Birch, Stewart, Kolasch & Birch, LLP
- 优先权： JP11-368123 19991224; JP11-368124 19991224
- 国际申请： PCT/JP00/09101 WO 20001221
- 国际公布： WO01/47547 WO 20010705
- 主分类号： A61K38/00
- IPC分类号： A61K38/00 ; A61K35/14 ; A61K35/16
摘要：
The present invention provides a pharmaceutical composition for treatment and prevention of bleeding disorders caused by platelet disorders, not caused by defect in blood coagulation factors or von Willebrand Factor but caused by reduction of circulating platelet count or platelet dysfunction, said composition comprising a hemostatic effective amount of Factor VIII and/or von Willebrand Factor. Also provided is a method for treating said bleeding, comprising administering a hemostatic effective amount of Factor VIII and/or von Willebrand Factor to patients suffering from bleeding disorders caused by platelet disorders.