发明授权
US07037712B2 DNA encoding ovine adenovirus (OAV287) and its use as a viral vector
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DNA编码腺病毒(OAV287)及其作为病毒载体的用途
- 专利标题: DNA encoding ovine adenovirus (OAV287) and its use as a viral vector
- 专利标题(中): DNA编码腺病毒(OAV287)及其作为病毒载体的用途
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申请号: US09464767申请日: 1999-12-16
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公开(公告)号: US07037712B2公开(公告)日: 2006-05-02
- 发明人: Gerald Wayne Both , David Bernard Boyle , Sadhanshu Vrati
- 申请人: Gerald Wayne Both , David Bernard Boyle , Sadhanshu Vrati
- 申请人地址: AU Victoria
- 专利权人: Commonwealth Scientific and Industrial Research Organisation
- 当前专利权人: Commonwealth Scientific and Industrial Research Organisation
- 当前专利权人地址: AU Victoria
- 代理机构: McDermott Will & Emery LLP
- 优先权: AUPM7101 19940726
- 主分类号: C12N15/861
- IPC分类号: C12N15/861 ; C07H21/04 ; A61K35/76 ; A61K48/00
摘要:
A genome of an ovine adenovirus designated OAV287 is isolated from sheep and sequenced. Portions of the genome not essential for maintenance or viability of the virus can be deleted or altered. A nucleotide sequence encoding a non-adenoviral polypeptide can be incorporated into the genome. The a full-length clone of the genome can be provided as part of a plasmid or viral vector. Cells can be transformed with a vector of the invention such that they express an exogenous protein.
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