An object, such as an example blood vessel, in a two or three dimensional image data set is segmented. An adaptable model, such as an example cylinder model, is defined around a starting point in the example blood vessel and is adapted or fit to the blood vessel. A plurality of candidate next active points are defined around the starting point and the adaptable model is defined around each candidate point. The models around the candidate points are adapted to the blood vessel. Based on results of the fitted models, a next active point is selected. In this manner, the blood vessel is segmented by adapting a series of cylinder models to an inner surface of the blood vessel.