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发明授权
US07045300B2 Lectin protein prepared from Maackia fauriei, process for preparing the same and the use thereof 有权
由麦草制备的凝集素蛋白，其制备方法及其用途

Lectin protein prepared from Maackia fauriei, process for preparing the same and the use thereof
摘要：
The present invention relates to a lectin protein, designated MFA isolated and purified from the bark of the Korean legume Maackia fauriei, process for preparing the same and the use thereof. This protein can be used as reagents in the study of carbohydrate binding proteins as well as to examine the distribution of N-acetylneuraminic acid in cancer cells owing to its capability that specifically recognizes N-acetylneuraminic acid which plays important structural and functional roles in the expressions of various cells or oligosaccharide terminal residue of glycoconjugates, and, in addition, used as an anti-cancer drug in view of its anti-proliferation effect against various cancers such as breast cancer, melanoma, hepatoma, etc.
摘要（中）：

本发明涉及一种从韩国豆科马鞭草的树皮分离和纯化的称为MFA的凝集素蛋白，其制备方法及其用途。 该蛋白质可用作碳水化合物结合蛋白的研究中的试剂，也可用于检查N-乙酰神经氨酸在癌细胞中的分布，因为其能够特异性识别N-乙酰神经氨酸，其在表达中起重要的结构和功能作用 的糖缀合物的各种细胞或寡糖末端残基，另外，鉴于其对各种癌症如乳腺癌，黑素瘤，肝癌等的抗增殖作用，另外用作抗癌药物。

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