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发明授权
US07049360B2 Water-soluble or water-dispersible (co) polymers of hydroxyalkyl (meth) acrylates, a process for their preparation, and their use as coating agent, binder and/or film-forming excipient pharmaceutical dosage forms 失效
（甲基）丙烯酸羟烷基酯的水溶性或水分散性（共）聚合物，其制备方法及其作为包衣剂，粘合剂和/或成膜赋形剂药物剂型的用途

  • 专利标题： Water-soluble or water-dispersible (co) polymers of hydroxyalkyl (meth) acrylates, a process for their preparation, and their use as coating agent, binder and/or film-forming excipient pharmaceutical dosage forms
  • 专利标题（中）： （甲基）丙烯酸羟烷基酯的水溶性或水分散性（共）聚合物，其制备方法及其作为包衣剂，粘合剂和/或成膜赋形剂药物剂型的用途
  • 申请号： US09964796
    申请日： 2001-09-28
  • 公开(公告)号： US07049360B2
    公开(公告)日： 2006-05-23
  • 发明人: Maximilian Angel , Axel Sanner , Karl Kolter
  • 申请人： Maximilian Angel , Axel Sanner , Karl Kolter
  • 申请人地址： DE Ludwigshafen
  • 专利权人： BASF Aktienegesellschaft
  • 当前专利权人： BASF Aktienegesellschaft
  • 当前专利权人地址： DE Ludwigshafen
  • 代理机构： Novak Druce & Quigg LLP
  • 代理商 Jason D. Voight
  • 优先权： DE10049297 20001004
  • 主分类号： C08K3/20
  • IPC分类号： C08K3/20
Water-soluble or water-dispersible (co) polymers of hydroxyalkyl (meth) acrylates, a process for their preparation, and their use as coating agent, binder and/or film-forming excipient pharmaceutical dosage forms
摘要：
The present invention relates to water-soluble or water-dispersible copolymers obtainable by free-radical polymerization of a) 80 to 20% by weight of hydroxy-C1–C6-alkyl (meth)acrylate and, where appropriate, one or more compounds of the formula (A) or (B) with R1=H, C1–C6-alkyl, R2=H, CH3 R3=C1–C24-alkyl or mixtures thereof in the presence of b) 20 to 80% by weight of polyvinyl alcohol (PVA) and c) where appropriate 0 to 20% by weight of other polymerizable compounds (C), a process for their preparation, and their use as coating agent, binder and/or film-forming excipient in pharmaceutical dosage forms.
摘要（中）：

本发明涉及通过自由基聚合得到的水溶性或水分散性共聚物，该共聚物是a）80-20％（重量）的羟基-C 1 -C 6 - - （甲基）丙烯酸烷基酯和（如果合适的话）一种或多种式（A）或（B）的化合物，其中R 1 = H，C 1 -C C 1 -C 6烷基，R 2 = H，CH 3 3 R 3 = C 1〜 -C 24 - - - 烷基或其混合物，b）20-80％（重量）的聚乙烯醇（PVA）和c）适当时0-20％重量的其它可聚合化合物（C ），其制备方法，以及它们作为药物剂型中的包衣剂，粘合剂和/或成膜赋形剂的用途。

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