发明授权
- 专利标题: MAGE-A3 peptides presented by HLA class II molecules
- 专利标题(中): 由HLA II类分子呈递的MAGE-A3肽
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申请号: US09860840申请日: 2001-05-18
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公开(公告)号: US07049413B2公开(公告)日: 2006-05-23
- 发明人: Yi Zhang , Pascal Chaux , Thierry Boon-Falleur , Pierre van der Bruggen
- 申请人: Yi Zhang , Pascal Chaux , Thierry Boon-Falleur , Pierre van der Bruggen
- 申请人地址: US NY New York
- 专利权人: Ludwig Institute for Cancer Research
- 当前专利权人: Ludwig Institute for Cancer Research
- 当前专利权人地址: US NY New York
- 代理机构: Wolf, Greenfield & Sacks, P.C.
- 主分类号: C07K14/435
- IPC分类号: C07K14/435 ; C07K7/00 ; C07K14/00
摘要:
The invention describes HLA class II binding peptides encoded by the MAGE-A3 tumor associated gene, as well as nucleic acids encoding such peptides and antibodies relating thereto. The peptides stimulate the activity and proliferation of CD4+ T lymphocytes. Methods and products also are provided for diagnosing and treating conditions characterized by expression of the MAGE-A3 gene.
公开/授权文献
- US20030049723A1 MAGE-A3 peptides presented by HLA class II molecules 公开/授权日:2003-03-13
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