- 专利标题： Inhibitors of IMPDH enzyme
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申请号： US10465425申请日： 2003-06-19
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公开(公告)号： US07053111B2公开(公告)日： 2006-05-30
- 发明人: Henry H. Gu , T. G. Murali Dhar , Edwin J. Iwanowicz
- 申请人： Henry H. Gu , T. G. Murali Dhar , Edwin J. Iwanowicz
- 申请人地址： US NJ Princeton
- 专利权人： Bristol-Myers Squibb Co.
- 当前专利权人： Bristol-Myers Squibb Co.
- 当前专利权人地址： US NJ Princeton
- 代理商 Laurelee A. Duncan; Maureen P. O'Brian; Audrey Sher
- 主分类号： A61K31/421
- IPC分类号： A61K31/421 ; A61K31/422 ; C07D263/32 ; C07D413/12
摘要：
The present invention discloses the identification of the novel inhibitors of IMPDH (inosine-5′-monophosphate dehydrogenase). The compounds and pharmaceutical compositions disclosed herein are useful in treating or preventing IMPDH associated disorders, such as transplant rejection and autoimmune diseases.
公开/授权文献
- US20040082562A1 Novel inhibitors of IMPDH enzyme 公开/授权日：2004-04-29