- 专利标题： Substituted pyridines as selective cyclooxygenase-2 inhibitors
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申请号： US10916097申请日： 2004-08-11
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公开(公告)号： US07060715B2公开(公告)日： 2006-06-13
- 发明人: Daniel Dube , Rejean Fortin , Richard Friesen , Zhaoyin Wang , Jacques Yves Gauthier
- 申请人： Daniel Dube , Rejean Fortin , Richard Friesen , Zhaoyin Wang , Jacques Yves Gauthier
- 申请人地址： CA Kirkland
- 专利权人： Merck Frosst Canada Ltd.
- 当前专利权人： Merck Frosst Canada Ltd.
- 当前专利权人地址： CA Kirkland
- 代理商 Raynard Yuro; David L. Rose
- 主分类号： C07D213/22
- IPC分类号： C07D213/22 ; C07D211/72 ; A61K31/435 ; A61K31/44
摘要：
The invention encompasses the novel compound of Formula I as well as a method of treating COX-2 mediated diseases comprising administration to a patient in need of such treatment of a non-toxic therapeutically effective amount of a compound of Formula I. The invention also encompasses certain pharmaceutical compositions for treatment of COX-2 mediated diseases comprising compounds of Formula I.