发明授权
- 专利标题： Proline derivatives and use thereof as drugs
- 专利标题（中）： 脯氨酸衍生物和作为药物的用途
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申请号： US11142523申请日： 2005-06-02
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公开(公告)号： US07060722B2公开(公告)日： 2006-06-13
- 发明人: Hiroshi Kitajima , Hiroshi Sakashita , Fumihiko Akahoshi , Yoshiharu Hayashi
- 申请人： Hiroshi Kitajima , Hiroshi Sakashita , Fumihiko Akahoshi , Yoshiharu Hayashi
- 申请人地址： JP Osaka
- 专利权人： Mitsubishi Pharma Corporation
- 当前专利权人： Mitsubishi Pharma Corporation
- 当前专利权人地址： JP Osaka
- 代理机构： Wenderoth, Lind & Ponack, L.L.P.
- 优先权： JP2000-243217 20000810; JP2000-400296 20001228
- 主分类号： A61K31/4025
- IPC分类号： A61K31/4025 ; A61K31/427
摘要：
The present invention aims at providing compounds having therapeutic effects due to a DPP-IV inhibitory action, and satisfactory as pharmaceutical products.The present inventors have found that derivatives having a substituent introduced into the γ-position of proline represented by the formula (I) wherein each symbol is as defined in the specification, have a potent DPP-IV inhibitory activity, and completed the present invention by increasing the stability.
公开/授权文献
- US20050245538A1 Proline derivatives and use thereof as drugs 公开/授权日：2005-11-03
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