发明授权
- 专利标题: Physiologically active peptide and its use
- 专利标题(中): 生理活性肽及其用途
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申请号: US09646078申请日: 1999-03-24
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公开(公告)号: US07064181B1公开(公告)日: 2006-06-20
- 发明人: Tetsuya Ohtaki , Hideki Matsui , Yoshihiro Ishibashi , Kazuhiro Ogi , Chieko Kitada
- 申请人: Tetsuya Ohtaki , Hideki Matsui , Yoshihiro Ishibashi , Kazuhiro Ogi , Chieko Kitada
- 申请人地址: JP Osaka
- 专利权人: Takeda Pharmaceutical Company Limited
- 当前专利权人: Takeda Pharmaceutical Company Limited
- 当前专利权人地址: JP Osaka
- 代理商 Mark Chao; Elaine M. Ramesh
- 优先权: JP10-078139 19980325; JP10-266972 19980921
- 国际申请: PCT/JP99/01482 WO 19990324
- 国际公布: WO99/48920 WO 19990930
- 主分类号: C07K14/00
- IPC分类号: C07K14/00
摘要:
The present invention relates to a peptide comprising an amino acid sequence identical to or substantially identical to an amino acid sequence represented by SEQ ID NO: 35 and having an ability of binding to a receptor protein comprising an amino acid sequence identical to or substantially identical to an amino acid sequence represented by SEQ ID NO: 1, SEQ ID NO: 2 or SEQ ID NO: 3, or a precursor thereof, its amide or ester, or a salt thereof.An inventive peptide-encoding DNA or equivalent can be employed in (1) a development of a receptor binding assay system using an expression system of a recombinant receptor protein and a screening for a pharmaceutical candidate compound, and (2) a development of a pharmaceutical having a reduced side effect such as a memory function improving agent, a appetite improving agent, an uterine, renal, prostatic, testicular or skeletal muscle function regulating agent.
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