- 专利标题: Dental products comprising bone growth enhancing peptide
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申请号: US10344046申请日: 2001-08-09
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公开(公告)号: US07078021B2公开(公告)日: 2006-07-18
- 发明人: Toshiyuki Yoneda , Motoyoshi Nomizu , Yoshinari Kumagai
- 申请人: Toshiyuki Yoneda , Motoyoshi Nomizu , Yoshinari Kumagai
- 申请人地址: US CA Hayward
- 专利权人: Acologix, Inc.
- 当前专利权人: Acologix, Inc.
- 当前专利权人地址: US CA Hayward
- 代理机构: Bozicevic, Field & Francis LLP
- 代理商 Karl Bozicevic
- 国际申请: PCT/US01/25101 WO 20010809
- 国际公布: WO02/13775 WO 20020221
- 主分类号: A61K7/16
- IPC分类号: A61K7/16 ; A61K38/00 ; C07K17/00
摘要:
Dental products such as toothpastes, mouthwash and dental floss are disclosed which products are enhanced by having dissolved, dispersed or coated thereon a compound which promoted bone growth. Preferred compounds are peptide sequences comprising 10 to 50 amino acids are disclosed. The sequences are characterized by containing an integrin binding motif such as RGD sequence and the remainder of amino acids contiguous with the RGD sequence in matrix extracellular phosphoglycoprotein. The sequences may be formulated for dispersed in toothpaste or a mouthwash and administered to enhance bone/tooth growth. When the dental products are used repeatedly over time they enhance good dental health.
公开/授权文献
- US20050002875A1 Dental products comprising bone growth enhancing peptide 公开/授权日:2005-01-06
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