发明授权
- 专利标题: 5-substituted isoquinoline derivatives
- 专利标题(中): 5-取代的异喹啉衍生物
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申请号: US10623751申请日: 2003-07-22
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公开(公告)号: US07094789B2公开(公告)日: 2006-08-22
- 发明人: Rintaro Yamada , Minoru Seto
- 申请人: Rintaro Yamada , Minoru Seto
- 申请人地址: JP Tokyo
- 专利权人: Asahi Kasei Pharma Corporation
- 当前专利权人: Asahi Kasei Pharma Corporation
- 当前专利权人地址: JP Tokyo
- 代理机构: Birch, Stewart, Kolasch & Birch, LLP
- 优先权: JP2002-212053 20020722; JP2002-327751 20021112
- 主分类号: C07D217/02
- IPC分类号: C07D217/02 ; A61K31/44
摘要:
A compound represented by the following formula (1) or a salt thereof: wherein R1 represents hydrogen atom, a halogen atom and the like; R2 represents hydrogen atom, a halogen atom, a C1-6 alkyl group and the like; and R3 represents —O—X—C(A1)(A11)-C(A2)(A21)-N(A31)(A3) (X represents propylene group etc., A11 and A21 represent hydrogen atom, or a C1-6 alkyl group, A31 represents a C1-6 alkyl group substituted with hydroxyl group, or hydrogen atom, and A1, A2, and A3 represent hydrogen atom, a C1-6 alkyl group and the like) and the like, which has an inhibitory activity on the phosphorylation of myosin regulatory light chain, and is useful for treatment of diseases relating to contraction of various cells and the like.
公开/授权文献
- US20050020623A1 5-Substituted isoquinoline derivatives 公开/授权日:2005-01-27
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