Invention Grant
- Patent Title: Pyrrolotriazine kinase inhibitors
- Patent Title (中): 吡咯并三嗪激酶抑制剂
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Application No.: US11152650Application Date: 2005-06-14
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Publication No.: US07102002B2Publication Date: 2006-09-05
- Inventor: Zhen-wei Cai , Louis J. Lombardo , Rajeev S. Bhide , Ligang Qian , Donna D. Wei , Stephanie Barbosa
- Applicant: Zhen-wei Cai , Louis J. Lombardo , Rajeev S. Bhide , Ligang Qian , Donna D. Wei , Stephanie Barbosa
- Applicant Address: US NJ Princeton
- Assignee: Bristol-Myers Squibb Company
- Current Assignee: Bristol-Myers Squibb Company
- Current Assignee Address: US NJ Princeton
- Agent Elliott Korsen
- Main IPC: C07D487/04
- IPC: C07D487/04 ; A61K31/53 ; A61P35/00
Abstract:
The present invention provides compounds of formula I, and pharmaceutically acceptable salts thereof. The formula I compounds inhibit the tyrosine kinase activity of growth factor receptors such as VEGFR-2 and FGFR-1, thereby making them useful as anti-cancer agents. The formula I compounds are also useful for the treatment of other diseases associated with signal transduction pathways operating through growth factor receptors.
Public/Granted literature
- US20060009454A1 Pyrrolotriazine kinase inhibitors Public/Granted day:2006-01-12
Information query
