发明授权
- 专利标题: FAIL molecules and uses thereof
- 专利标题(中): FAIL分子及其用途
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申请号: US10384850申请日: 2003-03-10
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公开(公告)号: US07109319B2公开(公告)日: 2006-09-19
- 发明人: Christopher C. Fraser
- 申请人: Christopher C. Fraser
- 申请人地址: US MA Cambridge
- 专利权人: Millennium Pharmaceuticals, Inc.
- 当前专利权人: Millennium Pharmaceuticals, Inc.
- 当前专利权人地址: US MA Cambridge
- 代理机构: Millennium Pharmaceuticals, Inc.
- 主分类号: C12N15/12
- IPC分类号: C12N15/12 ; C12N15/63 ; C12P21/00
摘要:
The invention provides isolated nucleic acid molecules, designated FAIL, which encode polypeptide molecules containing Ig and Ig-like domains and which are homologous to FcγRI. The invention also provides antisense nucleic acid molecules, expression vectors containing the nucleic acid molecules of the invention, host cells into which the expression vectors have been introduced, and non-human transgenic animals in which a nucleic acid molecule of the invention has been introduced or disrupted. The invention still further provides isolated polypeptides, fusion polypeptides, antigenic peptides and antibodies. Diagnostic, screening and therapeutic methods utilizing compositions of the invention are also provided.
公开/授权文献
- US20030175890A1 FAIL molecules and uses thereof 公开/授权日:2003-09-18
信息查询
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