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US07115717B2 Anti-TRAIL-R antibodies 失效
抗TRAIL-R抗体

Anti-TRAIL-R antibodies
摘要:
Anti-TRAIL-R1 and R2 antibodies or functional fragments thereof, having at least one property selected from the following (a) to (c) of:(a) having activity to induce apoptosis in carcinoma cells expressing TRAIL-R1 and/or TRAIL-R2;(b) not having effect on normal human cells expressing TRAIL-R1 and/or TRAIL-R2; and(c) not inducing human hepatocyte toxicity.
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