发明授权
- 专利标题： Method for increasing luminescence assay sensitivity
- 专利标题（中）： 增加发光测定灵敏度的方法
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申请号： US09590884申请日： 2000-06-09
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公开(公告)号： US07118878B1公开(公告)日： 2006-10-10
- 发明人: Erika Hawkins , John M. Centanni , Jacqueline Sankbeil , Keith V. Wood
- 申请人： Erika Hawkins , John M. Centanni , Jacqueline Sankbeil , Keith V. Wood
- 申请人地址： US WI Madison
- 专利权人： Promega Corporation
- 当前专利权人： Promega Corporation
- 当前专利权人地址： US WI Madison
- 代理机构： Schwegman, Lundberg, Woessner and Kluth P.A.
- 主分类号： C12Q1/66
- IPC分类号： C12Q1/66
摘要：
The invention provides kits and methods for increasing the sensitivity of a bio-luminescent assay, which employ an organic compound that, for instance, reduces luminescence that is not dependent on the presence of an analyte by at least about 10 fold and reduces luminescence that is dependent on the presence of an analyte by less than about 7 fold, reduces luminescence generated by luminogenic molecules not bound to an enzyme by at least about 10 fold and reduces the luminescence generated by luminogenic molecules bound to an enzyme by less than about 7 fold, or reduces autoluminescence by at least about 10 fold and reduces luminescence that is dependent on the presence of an analyte by less than about 7 fold.
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