发明授权
US07122576B2 Carbamate compounds for use in preventing or treating bipolar disorder
失效
用于预防或治疗双相情感障碍的氨基甲酸酯化合物
- 专利标题: Carbamate compounds for use in preventing or treating bipolar disorder
- 专利标题(中): 用于预防或治疗双相情感障碍的氨基甲酸酯化合物
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申请号: US10081606申请日: 2002-02-21
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公开(公告)号: US07122576B2公开(公告)日: 2006-10-17
- 发明人: Carlos R. Plata-Salaman , Boyu Zhao , Roy E. Twyman , Yong Moon Choi , Robert Gordon
- 申请人: Carlos R. Plata-Salaman , Boyu Zhao , Roy E. Twyman , Yong Moon Choi , Robert Gordon
- 主分类号: A01N47/10
- IPC分类号: A01N47/10 ; A61K31/27
摘要:
This invention is directed to a method for preventing or treating bipolar disorder comprising administering to a subject in need thereof a therapeutically effective amount of an enantiomer of Formula (I) or enantiomeric mixture wherein one enantiomer of Formula (I) predominates: wherein phenyl is substituted at X with one to five halogen atoms selected from the group consisting of fluorine, chlorine, bromine and iodine; and, R1, R2, R3 and R4 are independently selected from the group consisting of hydrogen and C1–C4 alkyl; wherein C1–C4 alkyl is optionally substituted with phenyl (wherein phenyl is optionally substituted with substituents independently selected from the group consisting of halogen, C1–C4 alkyl, C1–C4 alkoxy, amino, nitro and cyano).
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