Invention Grant
- Patent Title: Inhibitors of proteins that bind phosphorylated molecules
- Patent Title (中): 结合磷酸化分子的蛋白质的抑制剂
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Application No.: US10960344Application Date: 2004-10-07
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Publication No.: US07141596B2Publication Date: 2006-11-28
- Inventor: Andrew P. Combs , Eddy Wai Tsun Yue , Michael J. Bower , Wenyu Zhu , Matthew L. Crawley , Richard B. Sparks , James R. Pruitt , Amy Takvorian
- Applicant: Andrew P. Combs , Eddy Wai Tsun Yue , Michael J. Bower , Wenyu Zhu , Matthew L. Crawley , Richard B. Sparks , James R. Pruitt , Amy Takvorian
- Applicant Address: US DE Wilmington
- Assignee: Incyte Corporation
- Current Assignee: Incyte Corporation
- Current Assignee Address: US DE Wilmington
- Agency: Fish & Richardson P.C.
- Main IPC: A61K41/425
- IPC: A61K41/425 ; A61K31/4439 ; C07D275/02 ; C07D239/24 ; C07D417/04
Abstract:
The present invention provides compounds that can modulate the activity of a target protein, such as a phosphatase, that selectively binds phosphorylated peptides or proteins. The present compounds can be useful in treating diseases or disorders, including, for example, diabetes and obesity, that are connected directly or indirectly to the activity of the target protein.
Public/Granted literature
- US20050272778A1 Inhibitors of proteins that bind phosphorylated molecules Public/Granted day:2005-12-08
Information query
