A radiation image pick-up device which can restrain voltage fluctuations on GND and power supply lines, dispense with frame-by-frame wait periods, make possible stable and high speed moving image photographing, and are reduced in cost and dark current is to be provided.In pixels for detecting incident radiations, there are provided MIS-type conversion elements for converting the radiations into electric signals, source follower-type first TFTs for reading out the electric signals, second TFTs which so operate as to read out of the first TFTs the electric signals of the conversion elements selected by a drive circuit section on a row-by-row basis, and third TFTs which so operate as to reset or refresh on a row-by-row basis the conversion elements out of which reading by the first TFTs has been accomplished.