发明授权
- 专利标题： Enhanced circulation effector composition and method
- 专利标题（中）： 增强循环效应器组成和方法
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申请号： US10438502申请日： 2003-05-14
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公开(公告)号： US07160554B2公开(公告)日： 2007-01-09
- 发明人: Samuel Zalipsky , Martin C. Woodle , Francis J. Martin , Yechezkel Barenholz , Herve Bercovier
- 申请人： Samuel Zalipsky , Martin C. Woodle , Francis J. Martin , Yechezkel Barenholz , Herve Bercovier
- 申请人地址： US CA Mountain View
- 专利权人： ALZA Corporation
- 当前专利权人： ALZA Corporation
- 当前专利权人地址： US CA Mountain View
- 代理机构： Perkins Coie LLP
- 主分类号： A61K9/127
- IPC分类号： A61K9/127
摘要：
A liposome composition comprising small, surface-bound effector molecules is disclosed. The liposomes have a surface layer of hydrophilic polymer chains, for enhanced circulation time in the bloodstream. The effector molecules are attached to the distal ends of the polymer chains. In one embodiment, the effector is polymyxin B, for treatment of septic shock.
公开/授权文献
- US20030198665A1 Enhanced circulation effector composition and method 公开/授权日：2003-10-23
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