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发明授权
US07163941B2 Pyrido[2,3-d]pyrimidin-7-carboxylic acid derivatives, their manufacture and use as pharmaceutical agents 失效
吡啶并[2,3-d]嘧啶-7-甲酸衍生物，其制备和用作药剂

Pyrido[2,3-d]pyrimidin-7-carboxylic acid derivatives, their manufacture and use as pharmaceutical agents
摘要：
The invention describes compounds of the general formula I a process for their manufacture, medicaments containing them and their manufacture as well as the use of these compounds as pharmaceutically active agents. The compounds show activity as protein kinase inhibitors, in particular src family tyrosine kinase inhibitors, and may therefore be useful for the treatment of diseases mediated by said tyrosine kinases.
摘要（中）：

本发明描述了通式I的化合物，其制备方法，含有它们的药物及其制备以及这些化合物作为药物活性剂的用途。 化合物显示出作为蛋白激酶抑制剂，特别是src家族酪氨酸激酶抑制剂的活性，因此可用于治疗所述酪氨酸激酶介导的疾病。

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