发明授权
US07173040B2 Farnesyl transferase inhibiting 6-[(substituted phenyl)methyl]-quinoline and quinazoline derinazoline derivatives
有权
法呢基转移酶抑制6 - [(取代苯基)甲基] - 喹啉和喹唑啉衍生物衍生物
- 专利标题: Farnesyl transferase inhibiting 6-[(substituted phenyl)methyl]-quinoline and quinazoline derinazoline derivatives
- 专利标题(中): 法呢基转移酶抑制6 - [(取代苯基)甲基] - 喹啉和喹唑啉衍生物衍生物
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申请号: US10381556申请日: 2001-09-18
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公开(公告)号: US07173040B2公开(公告)日: 2007-02-06
- 发明人: Patrick René Angibaud , Marc Gaston Venet , Ashis Kumar Saha , Laurence Anne Mevellec
- 申请人: Patrick René Angibaud , Marc Gaston Venet , Ashis Kumar Saha , Laurence Anne Mevellec
- 申请人地址: BE
- 专利权人: Janssen Pharmaceutica N.V.
- 当前专利权人: Janssen Pharmaceutica N.V.
- 当前专利权人地址: BE
- 优先权: EP00203366 20000925
- 国际申请: PCT/EP01/10895 WO 20010918
- 国际公布: WO02/24683 WO 20020328
- 主分类号: C07D403/06
- IPC分类号: C07D403/06 ; A61K31/47 ; C07D215/227
摘要:
This invention comprises the compounds of formula (I): wherein r, s, t, Y1–Y2, R1, R2, R3, R4, R5, R6 and R7 have defined meanings, having farnesyl transferase inhibiting activity; their preparation, compositions containing them and their use as a medicine.
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