发明授权
- 专利标题： Nectin polypeptides
- 专利标题（中）： Nectin多肽
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申请号： US09972268申请日： 2001-10-05
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公开(公告)号： US07175849B2公开(公告)日： 2007-02-13
- 发明人: Peter R Baum , William C Fanslow, III , Timothy E Lofton , Eric A Sorensen , Adel Youakim
- 申请人： Peter R Baum , William C Fanslow, III , Timothy E Lofton , Eric A Sorensen , Adel Youakim
- 申请人地址： US CA Thousand Oaks
- 专利权人： Immunex Corporation
- 当前专利权人： Immunex Corporation
- 当前专利权人地址： US CA Thousand Oaks
- 代理商 Joseph R. Baker; Suzanne A. Sprunger; Susan E. Lingenfelter
- 主分类号： A61K39/00
- IPC分类号： A61K39/00 ; A61K38/04 ; C07K14/00
摘要：
This invention relates to nectin polypeptides and polynucleotides, to methods of making such polypeptides and polynucleotides, and to methods of using such polypeptides and polynucleotides to modulate cell adhesion, cell migration, and angiogenesis, to treat conditions related to cell adhesion including endothelial and epithelial cell proliferation, migration, and barrier function, and to identify agents that alter nectin polypeptide activities.