Invention Grant
US07179604B2 Methods of use of DNA encoding a human histamine receptor of the H3 subtype
有权
使用编码H3亚型的人组胺受体的DNA的方法
- Patent Title: Methods of use of DNA encoding a human histamine receptor of the H3 subtype
- Patent Title (中): 使用编码H3亚型的人组胺受体的DNA的方法
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Application No.: US10727021Application Date: 2003-12-02
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Publication No.: US07179604B2Publication Date: 2007-02-20
- Inventor: Timothy W. Lovenberg , Mark Erlander , Arne Huvar , Jayashree Pyati
- Applicant: Timothy W. Lovenberg , Mark Erlander , Arne Huvar , Jayashree Pyati
- Applicant Address: US NJ Raritan
- Assignee: Ortho-McNeil Pharmaceutical, Inc.
- Current Assignee: Ortho-McNeil Pharmaceutical, Inc.
- Current Assignee Address: US NJ Raritan
- Agency: Woodcock Washburn LLP
- Main IPC: C12Q1/68
- IPC: C12Q1/68 ; C07H21/02 ; C07H21/04
Abstract:
DNAs encoding the human histamine H3 receptor have been cloned and characterized. The recombinant protein is capable of forming biologically active histamine H3 receptor protein. The cDNA's have been expressed in recombinant host cells which produce active recombinant protein. The recombinant protein is also purified from the recombinant host cells. In addition, the recombinant host cells are utilized to establish a method for identifying modulators of the receptor activity, and receptor modulators are identified.
Public/Granted literature
- US20040156845A1 DNA encoding a human histamine receptor of the H3 subtype Public/Granted day:2004-08-12
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