The invention relates to a disk brake, in particular for utility vehicles, comprising a brake caliper, which extends over a brake disk, an application device located in the brake caliper for applying the brake pads on both sides of the brake disk in the direction of the latter, in addition to at least one adjusting system located in the brake caliper for compensating wear and tear on the brake pad and/or disk. The disk brake is characterized in that the adjusting system is configured on one or both sides of the brake disk as a preassembled adjuster module, which has at least the following components: an electromotor, which acts as the drive, or a drive connection to an electromotor and a reduction gear connected downstream of the electromotor, the rotative drive being fitted onto the mounting plate(s).