发明授权
US07183411B2 Naphthol, quinoline and isoquinoline-derived urea modulators of vanilloid VR1 receptor
有权
萘酚,喹啉和异喹啉衍生的凡士林VR1受体的尿素调节剂
- 专利标题: Naphthol, quinoline and isoquinoline-derived urea modulators of vanilloid VR1 receptor
- 专利标题(中): 萘酚,喹啉和异喹啉衍生的凡士林VR1受体的尿素调节剂
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申请号: US10616579申请日: 2003-07-10
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公开(公告)号: US07183411B2公开(公告)日: 2007-02-27
- 发明人: Ellen Codd , Scott L. Dax , Michele Jetter , Mark McDonnell , James J. McNally , Mark Youngman
- 申请人: Ellen Codd , Scott L. Dax , Michele Jetter , Mark McDonnell , James J. McNally , Mark Youngman
- 申请人地址: BE Beerse
- 专利权人: Janssen Pharmaceutica N.V.
- 当前专利权人: Janssen Pharmaceutica N.V.
- 当前专利权人地址: BE Beerse
- 主分类号: C07D217/22
- IPC分类号: C07D217/22 ; A61K31/47
摘要:
This invention is directed to vanilloid receptor VR1 ligands. More particularly, this invention relates to naphthol, quinoline and isoquinoline-derived ureas that are potent antagonists or agonists of VR1 which are useful for the treatment and prevention of inflammatory and other pain conditions in mammals.
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