发明授权
- 专利标题： Conformationally restricted polyamine analogs as disease therapies
- 专利标题（中）： 构象限制的多胺类似物作为疾病治疗
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申请号： US10873100申请日： 2004-06-21
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公开(公告)号： US07186825B2公开(公告)日： 2007-03-06
- 发明人: Benjamin Frydman , Laurence J. Marton , Venodhar K. Reddy , Aldonia L. Valasinas , Andrei V. Blokhin , Hirak S. Basu
- 申请人： Benjamin Frydman , Laurence J. Marton , Venodhar K. Reddy , Aldonia L. Valasinas , Andrei V. Blokhin , Hirak S. Basu
- 申请人地址： US CA Redwood City
- 专利权人： Cellgate, Inc.
- 当前专利权人： Cellgate, Inc.
- 当前专利权人地址： US CA Redwood City
- 代理机构： Morrison & Foerster, LLP
- 主分类号： C07C47/00
- IPC分类号： C07C47/00
摘要：
Novel conformationally restricted polyamine analogs are provided, as well as compositions comprising these novel polyamine analogs. Methods of using the novel polyamine analogs in treatment of diseases such as cancer are also provided. Also provided is a method of delivering these analogs specifically to tumor cells by covalently attaching polyamine analogs to porphyrin compounds, along with novel polyamine-porphyrin covalent conjugates.
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