A valve arrangement for providing clinical nutrition is provided. The valve arrangement is suitable for use with a rotary peristaltic pump and is capable of allowing flow of fluid in a first direction and capable of preventing flow of fluid in a second direction, wherein the valve arrangement comprises a valve having a cracking pressure of about 0.10 to about 0.20 bar. Also described are a method of production of the valve arrangement, use of the valve arrangement in providing nutrition to a patient and a method of treatment of a patient that comprises administering an effective amount of a composition via the valve arrangement.