发明授权
- 专利标题： Tripeptide and tetrapeptide sulfones
- 专利标题（中）： 三肽和四肽砜
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申请号： US11326975申请日： 2006-01-05
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公开(公告)号： US07192918B2公开(公告)日： 2007-03-20
- 发明人: Steven R. Schow , Natalia Aurrecoechea
- 申请人： Steven R. Schow , Natalia Aurrecoechea
- 申请人地址： US CA Palo Alto
- 专利权人： Telik, Inc.
- 当前专利权人： Telik, Inc.
- 当前专利权人地址： US CA Palo Alto
- 代理机构： Foley & Lardner LLP
- 主分类号： A61K38/06
- IPC分类号： A61K38/06 ; A61K38/07
摘要：
Tripeptide and tetrapeptide sulfones, pharmaceutical compositions containing them, their pharmaceutical use, and their preparation, are disclosed. The compounds are useful in potentiating the cytotoxic effects of chemotherapeutic agents in tumor cells, selectively exerting toxicity in tumor cells, elevating the production of GM progenitors in bone marrow cells, stimulating the differentiation of bone marrow, mitigating the myelosuppressive effects of chemotherapeutic agents, and modulating hematopoiesis in bone marrow.
公开/授权文献
- US20060148719A1 Tripeptide and tetrapeptide sulfones 公开/授权日：2006-07-06
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