发明授权
- 专利标题: Carbapenem compounds
- 专利标题(中): 碳青霉烯化合物
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申请号: US10494603申请日: 2002-11-01
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公开(公告)号: US07205291B2公开(公告)日: 2007-04-17
- 发明人: Makoto Sunagawa , Akira Sasaki
- 申请人: Makoto Sunagawa , Akira Sasaki
- 申请人地址: JP Osaka-Fu
- 专利权人: Dainippon Sumitomo Pharma Co., Ltd.
- 当前专利权人: Dainippon Sumitomo Pharma Co., Ltd.
- 当前专利权人地址: JP Osaka-Fu
- 代理机构: Wenderoth, Lind & Ponack, L.L.P.
- 优先权: JP2001-339195 20011105; JP2002-145485 20020520
- 国际申请: PCT/JP02/11477 WO 20021101
- 国际公布: WO03/040146 WO 20030515
- 主分类号: A61K31/397
- IPC分类号: A61K31/397 ; C07D487/06
摘要:
A compound or its pharmaceutically acceptable salt represented by the following formula: The invention is a carbapenem compound which has a potent antibacterial activity over a broad range of Gram negative and Gram positive bacteria, especially penicillin-resistant Streptococcus pneumoniae (PRSP) which has been isolated at an elevated frequency in recent years and thus causes a serious clinical problem, and Haemophilus influenzae which has acquired resistance against the existing β-lactam antibiotics over a wide scope due to penicillin-binding protein (PBP) mutations such as β-lactamase non-producing ampicillin-resistant (BLNAR) Haemophilus influenzae, and has excellent oral absorbability.
公开/授权文献
- US20050020566A1 Novel carbapenem compounds 公开/授权日:2005-01-27
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