发明授权
- 专利标题： CGRP receptor antagonists
- 专利标题（中）： CGRP受体拮抗剂
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申请号： US10551830申请日： 2004-04-09
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公开(公告)号： US07205292B2公开(公告)日： 2007-04-17
- 发明人: Christopher S. Burgey , Daniel V. Paone , Anthony W. Shaw , Theresa M. Williams
- 申请人： Christopher S. Burgey , Daniel V. Paone , Anthony W. Shaw , Theresa M. Williams
- 申请人地址： US NJ Rahway
- 专利权人： Merck & Co., Inc.
- 当前专利权人： Merck & Co., Inc.
- 当前专利权人地址： US NJ Rahway
- 代理商 David L. Rose; David Rubin
- 国际申请： PCT/US2004/011254 WO 20040409
- 国际公布： WO2004/091514 WO 20041028
- 主分类号： C07D405/14
- IPC分类号： C07D405/14 ; A61K31/4545 ; A61P25/06
摘要：
The present invention is directed to compounds of Formula I and Formula II: (where variables R1, R2, R3, R4, R6, A, B, G, J, W, X and Y are as defined herein) useful as antagonists of CGRP receptors and useful in the treatment or prevention of diseases in which the CGRP is involved, such as headache, migraine and cluster headache. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which CGRP is involved.
公开/授权文献
- US20060194783A1 Cgrp receptor antagonists 公开/授权日：2006-08-31