发明授权
US07214487B2 Methods for identifying compounds that modulate enzymatic activities by employing covalently bonded target-extender complexes with ligand candidates
有权
通过使用与配体候选物共价键合的靶向增殖物复合物鉴定调节酶活性的化合物的方法
- 专利标题: Methods for identifying compounds that modulate enzymatic activities by employing covalently bonded target-extender complexes with ligand candidates
- 专利标题(中): 通过使用与配体候选物共价键合的靶向增殖物复合物鉴定调节酶活性的化合物的方法
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申请号: US10374499申请日: 2003-02-25
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公开(公告)号: US07214487B2公开(公告)日: 2007-05-08
- 发明人: Daniel A. Erlanson , Robert S. McDowell , Stig Hansen
- 申请人: Daniel A. Erlanson , Robert S. McDowell , Stig Hansen
- 申请人地址: US CA South San Francisco
- 专利权人: Sunesis Pharmaceuticals, Inc.
- 当前专利权人: Sunesis Pharmaceuticals, Inc.
- 当前专利权人地址: US CA South San Francisco
- 代理机构: Heller Ehrman LLP
- 主分类号: C12Q1/68
- IPC分类号: C12Q1/68 ; C40B20/08 ; C40B50/08
摘要:
The present invention relates to methods for identifying compounds that modulate enzymatic activity by contacting covalently bonded PTP-extender complexes or modified covalently bonded PTP-extender complexes with ligand candidates.
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