发明授权
US07217734B2 Substituted benzopyrans as selective estrogen receptor-beta agonists
有权
取代的苯并吡喃作为选择性雌激素受体-β激动剂
- 专利标题: Substituted benzopyrans as selective estrogen receptor-beta agonists
- 专利标题(中): 取代的苯并吡喃作为选择性雌激素受体-β激动剂
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申请号: US10493092申请日: 2002-11-07
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公开(公告)号: US07217734B2公开(公告)日: 2007-05-15
- 发明人: Jeffrey Alan Dodge , Venkatesh Krishnan , Charles Willis Lugar, III , Blake Lee Neubauer , Bryan Hurst Norman , Lance Allen Pfeifer , Timothy Ivo Richardson
- 申请人: Jeffrey Alan Dodge , Venkatesh Krishnan , Charles Willis Lugar, III , Blake Lee Neubauer , Bryan Hurst Norman , Lance Allen Pfeifer , Timothy Ivo Richardson
- 申请人地址: US IN Indianapolis
- 专利权人: Eli Lilly and Company
- 当前专利权人: Eli Lilly and Company
- 当前专利权人地址: US IN Indianapolis
- 代理商 John C. Demeter
- 国际申请: PCT/US02/33622 WO 20021107
- 国际公布: WO03/044006 WO 20030530
- 主分类号: A61K31/35
- IPC分类号: A61K31/35
摘要:
The present invention relates to substituted benzopyran derivatives, stereoisomers, and pharmaceutical acceptable salts thereof and processes for the preparation of the same. The compounds of the present invention are useful as Estrogen Receptor β agonists. Such agonists are useful for the treating Estrogen Receptor β mediated diseases such as prostate cancer.
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