- 专利标题： Development of mutations useful for attenuating dengue viruses and chimeric dengue viruses
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申请号： US10719547申请日： 2003-11-21
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公开(公告)号： US07226602B2公开(公告)日： 2007-06-05
- 发明人: Stephen S. Whitehead , Brian R. Murphy , Kathryn A. Hanley , Joseph E. Blaney
- 申请人： Stephen S. Whitehead , Brian R. Murphy , Kathryn A. Hanley , Joseph E. Blaney
- 申请人地址： US DC Washington
- 专利权人： The United States of America, as represented by the Secretary, Department of Health and Human Services
- 当前专利权人： The United States of America, as represented by the Secretary, Department of Health and Human Services
- 当前专利权人地址： US DC Washington
- 代理机构： Knobbe, Martens, Olson & Bear, LLP
- 主分类号： A61K39/12
- IPC分类号： A61K39/12
摘要：
A menu of mutations was developed that is useful in fine-tuning the attenuation and growth characteristics of dengue virus vaccines.
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