Invention Grant
- Patent Title: Process for the preparation of rebeccamycin and analogs thereof
- Patent Title (中): 雷贝霉素及其类似物的制备方法
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Application No.: US10489625Application Date: 2002-09-13
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Publication No.: US07227019B2Publication Date: 2007-06-05
- Inventor: Jianji Wang
- Applicant: Jianji Wang
- Applicant Address: US NJ Princeton
- Assignee: Bristol-Myers Squibb Company
- Current Assignee: Bristol-Myers Squibb Company
- Current Assignee Address: US NJ Princeton
- Agent Elliot Korsen
- International Application: PCT/US02/29374 WO 20020913
- International Announcement: WO03/022861 WO 20030320
- Main IPC: C07H19/00
- IPC: C07H19/00 ; C07H19/22 ; C07G17/00 ; C07D487/00
Abstract:
The present invention relates to a method for making an indolopyrrolocarbazole of the general formula [I], where the method includes the step of reacting a bisindolylmaleimide compound with an oxidizing agent in the presence of an oxygen containing gas at a temperature and for a time sufficient to yield the indolopyrrolocarbazole compound of the general formula [I]. Methods of making rebeccamycin analogs using the indolopyrrolocarbazole compound are also provided
Public/Granted literature
- US20040248892A1 Process for the preparation of rebeccamycin and analogs thereof Public/Granted day:2004-12-09
Information query
