发明授权
- 专利标题： Benzo-fused heterocycles as endothelin antagonists
- 专利标题（中）： 苯并稠合的杂环作为内皮素拮抗剂
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申请号： US10486602申请日： 2002-07-31
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公开(公告)号： US07238685B2公开(公告)日： 2007-07-03
- 发明人: Martin Bolli , Christoph Boss , Martine Clozel , Walter Fischli , Thomas Weller , Judith Marfurt
- 申请人： Martin Bolli , Christoph Boss , Martine Clozel , Walter Fischli , Thomas Weller , Judith Marfurt
- 申请人地址： CH Allschwil
- 专利权人： Actelion Pharmaceuticals Ltd.
- 当前专利权人： Actelion Pharmaceuticals Ltd.
- 当前专利权人地址： CH Allschwil
- 代理机构： Dickstein Shapiro LLP
- 优先权： EPPCT/EP01/09235 20010809
- 国际申请： PCT/EP02/08523 WO 20020731
- 国际公布： WO03/013545 WO 20030220
- 主分类号： C07D243/24
- IPC分类号： C07D243/24 ; C07D217/16 ; C07D401/12 ; A61K31/5513 ; A61P19/00
摘要：
The invention relates to novel benzo-fused heterocycles and their use as active ingredients in the preparation of pharmaceutical compositions. The invention also concerns related aspects including processes for the preparation of the compounds, pharmaceutical compositions containing one or more of those compounds and especially their use as endothelin receptor antagonists.
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