发明授权
- 专利标题： Polynucleotides and polypeptides associated with the development of rheumatoid arthritis
- 专利标题（中）： 与类风湿性关节炎发展相关的多核苷酸和多肽
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申请号： US10308279申请日： 2002-12-03
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公开(公告)号： US07244573B2公开(公告)日： 2007-07-17
- 发明人: Julie Carman , Steven G. Nadler , Michael Bowen , Michael G. Neubauer , Pin Lu
- 申请人： Julie Carman , Steven G. Nadler , Michael Bowen , Michael G. Neubauer , Pin Lu
- 申请人地址： US NJ Princeton
- 专利权人： Bristol-Myers Squibb Company
- 当前专利权人： Bristol-Myers Squibb Company
- 当前专利权人地址： US NJ Princeton
- 代理商 Nickki L. Parlet
- 主分类号： G01N33/53
- IPC分类号： G01N33/53 ; G01N33/564 ; C07H21/04
摘要：
The present invention is directed to polynucleotides encoding polypeptides associated with the development of rheumatoid arthritis and homologs thereof. The invention further relates to diagnostic and therapeutic methods for utilizing these polynucleotides and polypeptides in the diagnosis, treatment, and/or prevention of rheumatoid arthritis and related disease states. The invention further relates to screening methods for identifying agonists and antagonists of the polynucleotides and polypeptides of the present invention, and compounds identified thereby.