发明授权
US07244721B2 Peptides as NS3-serine protease inhibitors of hepatitis C virus
有权
肽作为丙型肝炎病毒的NS3-丝氨酸蛋白酶抑制剂
- 专利标题： Peptides as NS3-serine protease inhibitors of hepatitis C virus
- 专利标题（中）： 肽作为丙型肝炎病毒的NS3-丝氨酸蛋白酶抑制剂
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申请号： US10052386申请日： 2002-01-18
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公开(公告)号： US07244721B2公开(公告)日： 2007-07-17
- 发明人: Anil K. Saksena , Viyyoor Moopil Girijavallabhan , Raymond G. Lovey , Edwin Jao , Frank Bennett , Jinping L. Mc Cormick , Haiyan Wang , Russell E. Pike , Stephane L. Bogen , Tin-Yau Chan , Yi-Tsung Liu , Zhaoning Zhu , F. George Njoroge , Ashok Arasappan , Tejal Parekh , Ashit K. Ganguly , Kevin X. Chen , Srikanth Venkatraman , Henry A. Vaccaro , Patrick A. Pinto , Bama Santhanam , Scott Jeffrey Kemp , Odile Esther Levy , Marguerita Lim-Wilby , Susan Y. Tamura , Wanli Wu , Siska Hendrata , Yuhua Huang , Jesse K. Wong , Latha G. Nair
- 申请人： Anil K. Saksena , Viyyoor Moopil Girijavallabhan , Raymond G. Lovey , Edwin Jao , Frank Bennett , Jinping L. Mc Cormick , Haiyan Wang , Russell E. Pike , Stephane L. Bogen , Tin-Yau Chan , Yi-Tsung Liu , Zhaoning Zhu , F. George Njoroge , Ashok Arasappan , Tejal Parekh , Ashit K. Ganguly , Kevin X. Chen , Srikanth Venkatraman , Henry A. Vaccaro , Patrick A. Pinto , Bama Santhanam , Scott Jeffrey Kemp , Odile Esther Levy , Marguerita Lim-Wilby , Susan Y. Tamura , Wanli Wu , Siska Hendrata , Yuhua Huang , Jesse K. Wong , Latha G. Nair
- 申请人地址： US NJ Kenilworth US WA Seattle
- 专利权人： Schering Corporation,Dendreon Corporation
- 当前专利权人： Schering Corporation,Dendreon Corporation
- 当前专利权人地址： US NJ Kenilworth US WA Seattle
- 代理机构： Lerner, David, Littenberg, Krumholz & Mentlik, LLP
- 代理商 Palaiyur S. Kalyanaraman
- 主分类号： A61K31/497
- IPC分类号： A61K31/497 ; A61K31/407 ; A61K31/454 ; A61K31/4025
摘要：
The present invention discloses novel compounds which have HCV protease inhibitory activity as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising such compounds as well as methods of using them to treat disorders associated with the HCV protease.